New Long-Acting diabetes shot shows promise in first human test

NCT ID NCT06439056

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early study tested a single injection of NEX-22A, a long-acting version of the diabetes drug liraglutide, in 12 adults with type 2 diabetes. The main goal was to see how the drug moves through the body and if it is safe. Participants were on stable metformin therapy and received one dose. Results will help decide if further testing is warranted.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

NEX-22A (a long-acting form of liraglutide)

What this could lead to

If successful, this could lead to a once-weekly or less frequent injection for managing type 2 diabetes, improving convenience for patients.

What could go wrong

This is a very early Phase 1 study with only 12 participants, so it is too small to prove effectiveness or safety. The drug may not work as hoped or could cause unexpected side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Profil

    Neuss, 41460, Germany