New antibody weapons target debilitating bowel disease

NCT ID NCT07012395

Recruiting now Disease control Sponsor: Spyre Therapeutics, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing several long-acting antibody treatments, both alone and in combinations, for adults with moderate to severe ulcerative colitis. The goal is to see if these treatments can control the disease by reducing inflammation and symptoms. The trial will involve 645 participants and compare the new treatments against a placebo to determine their effectiveness and safety.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

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Miami, Florida, 33165, United States

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Chapel Hill, North Carolina, 27599, United States

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Site 002
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San Antonio, Texas, 78229, United States

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Site 003
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Boston, Massachusetts, 02114, United States

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Site 005
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Garland, Texas, 75246, United States

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Site 006
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Kansas City, Kansas, 66160, United States

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Site 007
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Kissimmee, Florida, 34741, United States

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Site 008
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Southlake, Texas, 76092, United States

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Site 009
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Webster, Texas, 77598, United States

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Site 011
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Glen Burnie, Maryland, 21061, United States

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Site 012
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Lancaster, California, 93534, United States

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Site 013
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Cedar Park, Texas, 78613, United States

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Site 016
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Winston-Salem, North Carolina, 27103, United States

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Site 017
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Kingsport, Tennessee, 37663, United States

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Site 019
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Tacoma, Washington, 98405, United States

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Site 023
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La Jolla, California, 92037, United States

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Site 024
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Canoga Park, California, 91304, United States

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Site 025
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Providence, Rhode Island, 02904, United States

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Site 028
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Rochester, Minnesota, 55905, United States

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Site 033
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Colorado Springs, Colorado, 91304, United States

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Site 035
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Marrero, Louisiana, 70072, United States

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Site 083
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London, Ontario, G8H 3P7, Canada

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Site 085
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Greater Sudbury, P3C1X3, Canada

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Site 086
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London, N6K 1M6, Canada

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Site 202
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Heidelberg, 3084, Australia

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Site 204
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Liverpool, 2170, Australia

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Site 206
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South Brisbane, 4101, Australia

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Site 207
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Woolloongabba, 4102, Australia

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Site 208
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Concord, 2139, Australia

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Site 351
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Seoul, 03722, South Korea

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Site 352
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Seoul, 06591, South Korea

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Site 353
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Wŏnju, 26426, South Korea

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Site 354
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Daegu, 40404, South Korea

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Site 355
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Daejeon, 34943, South Korea

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Site 356
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Seoul, 03312, South Korea

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Site 357
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Busan, 48108, South Korea

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Site 358
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Daegu, 42415, South Korea

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Site 359
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Suwon, 16247, South Korea

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Site 360
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Seoul, 07985, South Korea

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Site 361
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Daegu, 42601, South Korea

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Site 362
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Seoul, 6351, South Korea

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Site 391
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Taipei, 100225, Taiwan

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Site 392
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Chiayi City, 600, Taiwan

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Site 393
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Taoyuan, 333, Taiwan

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Site 394
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Changhua, 500, Taiwan

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Site 396
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Taichung, 404327, Taiwan

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Site 397
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Taipei, 104, Taiwan

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Site 441
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Beersheba, 8410101, Israel

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Site 442
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Nahariya, 2210001, Israel

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Site 443
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Haifa, 31048, Israel

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Site 444
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Jerusalem, 9103102, Israel

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Site 445
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Beer Yaaqov, 7033001, Israel

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Site 446
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Jerusalem, 9112001, Israel

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Site 463
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Linz, 4021, Austria

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Site 481
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Banja Luka, 78 000, Bosnia and Herzegovina

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Site 483
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Sarajevo, 71000, Bosnia and Herzegovina

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Site 484
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Mostar, 88000, Bosnia and Herzegovina

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Site 492
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Sofia, 1343, Bulgaria

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Site 531
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Brno, 615 00, Czechia

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Site 581
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Tbilisi, 0102, Georgia

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Site 582
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Tbilisi, 0159, Georgia

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Site 583
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Tbilisi, 01444, Georgia

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Site 584
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Kutaisi, 4600, Georgia

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Site 585
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Tbilisi, 0180, Georgia

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Site 586
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Tbilisi, 0144, Georgia

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Site 587
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Tbilisi, 0159, Georgia

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Site 588
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Tbilisi, 0114, Georgia

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Site 589
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Marneuli, 3000, Georgia

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Site 590
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Tbilisi, 0178, Georgia

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Site 604
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Berlin, 14163, Germany

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Site 634
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Athens, 10676, Greece

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Site 652
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Székesfehérvár, H-8000, Hungary

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Site 711
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Chisinau, MD2025, Moldova

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Site 712
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Chisinau, MD2025, Moldova

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Chisinau, MD2005, Moldova

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Chisinau, MD2025, Moldova

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Site 715
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Chisinau, MD2068, Moldova

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Site 731
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Warsaw, 04-501, Poland

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Site 732
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Bydgoszcz, 85-794, Poland

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Site 733
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Szczecin, 71-685, Poland

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Site 734
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Wroclaw, 53-149, Poland

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Site 735
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Katowice, 40-748, Poland

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Site 736
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Rzeszów, 35-326, Poland

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Site 737
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Szczecin, 71-434, Poland

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Site 738
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Wroclaw, 52-416, Poland

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Site 739
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Warsaw, 00--710, Poland

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Site 741
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Warsaw, 02-786, Poland

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Site 742
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Wroclaw, 54-239, Poland

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Site 743
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Opole, 45-819, Poland

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Site 744
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Sopot, 81-756, Poland

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Site 745
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Staszów, 28-2200, Poland

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Site 747
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Wroclaw, 53-611, Poland

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Site 748
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Krakow, 31-501, Poland

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Site 750
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Warsaw, 57-300, Poland

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Site 751
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Warsaw, 00-189, Poland

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Site 752
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Tychy, 43-100, Poland

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Site 753
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Bydgoszcz, 85-2299, Poland

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Site 754
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Warsaw, 02-172, Poland

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Site 801
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Zrenjanin, 23000, Serbia

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Site 802
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Belgrade, 11000, Serbia

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Site 803
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Belgrade, 11080, Serbia

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Site 805
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Niš, 18 000, Serbia

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Site 806
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Užice, 31000, Serbia

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Site 807
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Belgrade, 11000, Serbia

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Site 821
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Prešov, 080 01, Slovakia

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Site 822
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Košice, 040 13, Slovakia

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Site 823
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Bratislava, 811 09, Slovakia

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Site 825
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Zvolen, 960 01, Slovakia

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Site 834
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Madrid, 28031, Spain

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Site 836
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Ourense, 32005, Spain

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Site 837
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Madrid, 28222, Spain

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Site 851
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Sankt Gallen, 9007, Switzerland

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Site 852
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Basel, 4031, Switzerland

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Site 853
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Bern, 3012, Switzerland

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Site 901
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Lutsk, 43005, Ukraine

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Site 902
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Kyiv, 02002, Ukraine

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Site 903
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Kyiv, 04210, Ukraine

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Site 904
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Kyiv, 02091, Ukraine

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Site 905
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Kyiv, 03037, Ukraine

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Site 906
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Ivano-Frankivsk, 76008, Ukraine

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Site 907
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Vinnytsia, 21029, Ukraine

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Site 908
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Vinnytsia, 21009, Ukraine

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Site 909
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Lviv, 79010, Ukraine

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Site 910
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Vinnytsia, 21028, Ukraine

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Site 911
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Kyiv, 04107, Ukraine

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Site 912
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Lviv, 79059, Ukraine

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Site 913
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Kyiv, 04050, Ukraine

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Site 914
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Poltava, 36011, Ukraine

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Trial Site 804
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Belgrade, 11 000, Serbia

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Conditions

Explore the condition pages connected to this study.

COLITIS COLITIS, ULCERATIVE INFLAMMATORY BOWEL DISEASES ULCERATIVE COLITIS