New imaging agent could sharpen prostate cancer staging

NCT ID NCT06122584

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 3 trial is testing whether a radioactive tracer called [18F]PSMA-1007 can improve PET/CT scans for men with newly diagnosed high-risk or very-high-risk prostate cancer. The goal is to see if it can more accurately detect cancer that has spread to pelvic lymph nodes. About 380 men will receive the tracer before undergoing prostate removal surgery, and the scan results will be compared with tissue samples.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

[18F]PSMA-1007 (a radioactive tracer for PET scans)

What this could lead to

If successful, this could provide a more accurate way to detect cancer spread in lymph nodes, helping doctors plan better treatment for high-risk prostate cancer.

What could go wrong

This is a diagnostic study, not a treatment. The tracer may not prove more accurate than current methods, and results depend on comparison with surgical tissue samples.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate adenocarcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHRU de Nancy

    RECRUITING

    Nancy, France

  • CWZ

    RECRUITING

    Nijmegen, Netherlands

  • Carl Gustav Carus Faculty of Medicine, TUD Dresden

    RECRUITING

    Dresden, Germany

  • Hospital Del Mar

    RECRUITING

    Barcelona, Spain

  • Hospital Vall d'Hebron

    RECRUITING

    Barcelona, Spain

  • Hospital Vithas Valencia 9 de Octubre

    ACTIVE_NOT_RECRUITING

    Valencia, Spain

  • IRCCS Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori"

    RECRUITING

    Meldola, Italy

  • IRCCS Ospedale Sacro Cuore-Don Calabria

    RECRUITING

    Verona, Italy

  • Klinikum rechts der Isar, TUM

    ACTIVE_NOT_RECRUITING

    München, Germany

  • National Cancer Center

    RECRUITING

    Tokyo, Japan

  • Radboud UMC

    RECRUITING

    Nijmegen, Netherlands

  • St. Antonius Hospital

    RECRUITING

    Gronau, Germany

  • The University of Osaka Hospital

    RECRUITING

    Osaka, Japan

  • University Hospital Düsseldorf

    RECRUITING

    Düsseldorf, Germany

  • University Hospital Hamburg-Eppendorf

    RECRUITING

    Hamburg, Germany

  • University Hospital Leipzig

    RECRUITING

    Leipzig, Germany

  • University Hospital Münster

    RECRUITING

    Münster, Germany

  • Universitätsmedizin Rostock

    RECRUITING

    Rostock, Germany