New PET/MRI scan aims to find hidden brain tumor cells

NCT ID NCT05632562

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase study tests a new type of PET/MRI scan that uses special radioactive tracers to detect leftover high grade glioma (a fast-growing brain cancer) after standard radiation therapy. About 20 patients aged 10 and older will receive up to three imaging sessions. The goal is to see if the scan can find active tumor that standard imaging might miss, and to develop a workflow for future use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

O-(2-[18F]Fluoroethyl)-L-tyrosine (FET) and 1H-1-(3-[18F]fluoro-2-hydroxypropyl)-2-nitroimidazole (FMISO) radioactive tracers

What this could lead to

If successful, this imaging method could help doctors better detect leftover tumor after standard treatment, potentially guiding more personalized care.

What could go wrong

This is a very early feasibility study with only 20 participants, so results may not apply widely. The scan is experimental and not yet proven to improve outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

glioma malignant glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UAB

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35249, United States

  • UAB

    RECRUITING

    Birmingham, Alabama, 35249, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••