New pill targets 'Undruggable' cancer mutation in multiple tumor types

NCT ID NCT04956640

Recruiting now Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

Summary

This study is testing an experimental pill called LY3537982 for people with advanced cancers that have a specific genetic change called KRAS G12C. The research aims to find the safest and most effective dose, both alone and combined with other cancer drugs, for patients with lung, colorectal, pancreatic, and several other cancers. Most participants have already tried standard treatments, though some groups with untreated lung cancer may also qualify.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

AdventHealth Orlando
RECRUITING

Orlando, Florida, 32803, United States
Aichi Cancer Center Hospital
RECRUITING

Nagoya, Aichi-ken, 464-8681, Japan
Asan Medical Center
RECRUITING

Seoul, Korea, 05505, South Korea
Cancer Research SA
RECRUITING

Adelaide, South Australia, 5000, Australia
Centre Leon Berard
RECRUITING

Lyon, Auvergne-Rhône-Alpes, 69008, France
Chao Family Comprehensive Cancer Ctr.
RECRUITING

Orange, California, 92868, United States
Chonnam National University Hwasun Hospital
RECRUITING

Hwasun-gun, Jeonranamdo, 58128, South Korea
Community Health Network
RECRUITING

Indianapolis, Indiana, 46250, United States
Cross Cancer Institute
RECRUITING

Edmonton, Alberta, T6G 1Z2, Canada
Dartmouth-Hitchcock Medical Center
RECRUITING

Lebanon, New Hampshire, 03756, United States
Florida Cancer Specialists
RECRUITING

Sarasota, Florida, 34236, United States
Fox Chase Cancer Center
RECRUITING

Philadelphia, Pennsylvania, 19111-2497, United States
Gustave Roussy
RECRUITING

Villejuif, 94805, France
Hokkaido University Hospital
RECRUITING

Sapporo, Hokkaido, 060-8648, Japan
Indiana Univ Melvin & Bren Simon Cancer Center
RECRUITING

Indianapolis, Indiana, 46202, United States
Inova Health System IRB
RECRUITING

Fairfax, Virginia, 22031, United States
Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest
RECRUITING

Bordeaux, Aquitaine, 33076, France
Institut Claudius Regaud - IUCT Oncopole
RECRUITING

Toulouse, 31052, France
Institut du Cancer de Montpellier - Val d'aurelle
RECRUITING

Montpellier, 34298, France
Kanazawa University Hospital
RECRUITING

Kanazawa, Ishikawa-ken, 920, Japan
Linear Clinical Research
RECRUITING

Nedlands, Western Australia, 6009, Australia
Mary Bird Perkins Cancer Center
RECRUITING

Baton Rouge, Louisiana, 70809, United States
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States
NYU Langone
RECRUITING

New York, New York, 10016, United States
NYU Langone Health- Long Island
RECRUITING

Mineola, New York, 11501, United States
National Cancer Center
RECRUITING

Goyang-si, Gyeonggi-do, 10408, South Korea
National Cancer Center Hospital
RECRUITING

Chuo-ku, Tokyo, 104-0045, Japan
National Cancer Center Hospital East
RECRUITING

Kashiwa, Chiba, 277-8577, Japan
Novant Health Cancer Institute - Elizabeth
RECRUITING

Charlotte, North Carolina, 28204, United States
Novant Health Cancer Institute - Forsyth
RECRUITING

Winston-Salem, North Carolina, 27103, United States
Peninsula and Southeast Oncology
RECRUITING

Frankston, Victoria, 3199, Australia
Princess Margaret Hospital (Ontario)
RECRUITING

Toronto, Ontario, M4X 1K9, Canada
Royal North Shore Hospital
RECRUITING

St Leonards, New South Wales, 2065, Australia
START Mountain Region
RECRUITING

West Valley City, Utah, 84119, United States
Sarah Cannon Cancer Center
RECRUITING

Nashville, Tennessee, 37203, United States
Seoul National University Hospital
RECRUITING

Seoul, Korea, 03080, South Korea
South Texas Accelerated Research Therapeutics (START)
RECRUITING

San Antonio, Texas, 78229-3307, United States
St Vincent's Hospital Sydney
RECRUITING

Sydney, New South Wales, 2010, Australia
The Catholic University of Korea, St. Vincent's Hospital
RECRUITING

Suwon, Gyeonggi-do, 16247, South Korea
The University of North Carolina at Chapel Hill
RECRUITING

Chapel Hill, North Carolina, 27599, United States
UPMC Hillman Cancer Center
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
USC Norris Cancer Hospital
RECRUITING

Los Angeles, California, 90033, United States
USO-Virginia Cancer Specialists, PC
RECRUITING

Fairfax, Virginia, 22031, United States
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35233, United States
University of Wisconsin-Madison Hospital and Health Clinic
RECRUITING

Madison, Wisconsin, 53792-4108, United States
Vanderbilt Univeristy School of Medicine
RECRUITING

Nashville, Tennessee, 37212-6303, United States
Wakayama Medical University Hospital
RECRUITING

Wakayama, 641-8510, Japan
Yale-New Haven Hospital
RECRUITING

New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

BILIARY TRACT NEOPLASMS CARCINOMA, NON-SMALL-CELL LUNG COLORECTAL NEOPLASMS ENDOMETRIAL NEOPLASMS OVARIAN NEOPLASMS PANCREATIC NEOPLASMS