Brain infusion upgrade: could a new method make Parkinson's treatment easier?
NCT ID NCT07215403
First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 2 times
Summary
This study tests a new, faster method to deliver the drug AB-1005 into the brain of people with advanced Parkinson's disease. The goal is to see if the new approach can consistently reach the target area while being safer and quicker. 18 participants will be enrolled to assess the procedure's accuracy and safety over 6 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- AB-1005 (a drug delivered directly into the brain)
- What this could lead to
- If successful, this could make brain infusions for Parkinson's quicker and more reliable, potentially improving treatment delivery.
- What could go wrong
- This is a small, early-stage trial focused on the delivery method, not on whether the drug itself works. The procedure still carries risks like bleeding or infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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The Ohio State University Wexner Medical Center Neurological Surgery
Columbus, Ohio, 43210, United States
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University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could your own bone marrow cells help fight Parkinson's?
- Could gut microbes hold clues to Parkinson's?
- Brain implant for Parkinson's may raise fall risk — a study investigates
- Could hand exercises sharpen the mind in Parkinson's?
- Which balance test best predicts falls in Parkinson's? a head-to-head comparison