New hope for Tough-to-Treat colon cancer?

NCT ID NCT05678257

Terminated Disease control Sponsor: NuCana plc Source: ClinicalTrials.gov ↗

Summary

This study tested a new drug combination (NUFIRI-bev) against the standard treatment (FOLFIRI-bev) for people with advanced colorectal cancer that had spread and could not be removed by surgery. The goal was to see if the new combination was more effective and safer for patients whose cancer had worsened after initial treatment. The trial was terminated before completion.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Azienda Ospedaliera Regionale San Carlo

Potenza, 85100, Italy
Azienda Ospedaliera Universitaria - Università degli Studi della Campania Luigi Vanvitelli

Naples, Campania, 80131, Italy
Azienda Ospedaliero Universitaria Careggi

Florence, Tuscany, 50134, Italy
Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona

Ancona, 60126, Italy
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda

Milan, 20162, Italy
Barbara Ann Karmanos Cancer Institute

Detroit, Michigan, 48201, United States
Boston Medical Center

Boston, Massachusetts, 02118, United States
Cancer Center of Kansas

Wichita, Kansas, 67214, United States
Centre Georges-François Leclerc

Dijon, Bourgogne-Franche-Comté, 21079, France
Centre Hospitalier Régional et Universitaire de Besançon - Hôpital Jean-Minjoz

Besançon, Doubs, 25000, France
Centre Hospitalier Universitaire de Poitiers

Poitiers, Vienne, 86000, France
Centre Hospitalier UniversitaireNantes - Hôtel Dieu

Nantes, 44000, France
Charité Campus Virchow-Klinikum

Berlin, 13353, Germany
Complejo Hospitalario Universitario de Santiago (CHUS)

Santiago de Compostela, La Coruña, 15706, Spain
Fondazione IRCCS Istituto Nazionale dei Tumori

Milan, Lombardy, 20133, Italy
Fred Hutchinson Cancer Center at Evergreen Health

Kirkland, Washington, 98034, United States
Georgetown University Medical Center

Washington D.C., District of Columbia, 20007, United States
Guy's and Saint Thomas' NHS Foundation Trust

London, Greater London, SE1 9RT, United Kingdom
Helen F. Graham Cancer Center

Newark, Delaware, 19713, United States
Hospital Duran i Reynals

Barcelona, 8908, Spain
Hospital General Universitario Gregorio Marañón

Madrid, 28007, Spain
Hospital Universitari Arnau de Vilanova

Lleida, 25198, Spain
Hospital Universitari Vall d'Hebrón

Barcelona, 8035, Spain
Hospital Universitario 12 de Octubre

Madrid, 28041, Spain
Hospital Universitario Fundación Alcorcón

Alcorcón, Madrid, 28922, Spain
Hospital Universitario Puerta de Hierro

Majadahonda, Madrid, 28222, Spain
Hospital Universitario Virgen de la Victoria

Málaga, 29010, Spain
Hospital Universitario Virgen del Rocío

Seville, 41013, Spain
Hospital de León

León, 24008, Spain
Hospital de la Santa Creu i Sant Pau

Barcelona, 08041, Spain
Hôpital Européen Georges-Pompidou

Paris, Île-de-France Region, 75015, France
Hôpital Européen Marseille

Marseille, Bouches-du-Rhône, 13003, France
Hôpital Foch

Suresnes, Île-de-France Region, 92150, France
Institut Bergonié

Bordeaux, Gironde, 33076, France
Institut Català d'Oncologia - ICO Badalona - Hospital Universitari Germans Trias i Pujol

Badalona, Barcelona, 08916, Spain
Istituto Oncologico Veneto - IRCCS

Padua, Veneto, 35128, Italy
Krankenhaus Nordwest

Frankfurt am Main, Hesse, 60488, Germany
MD Anderson Cancer Center Madrid

Madrid, 28033, Spain
Morristown Medical Center

Morristown, New Jersey, 07960, United States
Mount Vernon Cancer Centre - East and North Hertfordshire NHS Trust

Northwood, Middlesex, HA6 2RN, United Kingdom
München Klinik Neuperlach

München, Bavaria, 81737, Germany
NHS Greater Glasgow and Clyde

Glasgow, G51 4TF, United Kingdom
Northwest Cancer Specialists, P.C. dba Compass Oncology - Vancouver Cancer Center

Vancouver, Washington, 98684, United States
Norton Cancer Institute

Louisville, Kentucky, 40202, United States
Ospedale Santa Maria delle Croci di Ravenna

Faenza, Ravenna, 48121, Italy
Queen's Hospital

Romford, Essex, RM7 OAG, United Kingdom
Royal Free London NHS Foundation Trust

London, Greater London, NW3 2QG, United Kingdom
Strasbourg Oncology Liberale - Clinique Sainte-Anne

Strasbourg, Alsace, 67000, France
Texas Oncology - Baylor Charles A. Sammons Cancer Center

Dallas, Texas, 75246, United States
The Christ Hospital Cancer Center

Cincinnati, Ohio, 45219, United States
The Christie NHS Foundation Trust

Manchester, Lancashire, M20 4BX, United Kingdom
USOR - Texas Oncology Northeast Texas

Tyler, Texas, 75702, United States
University College London Hospitals NHS Foundation Trust

London, Greater London, NW1 2PG, United Kingdom
University of Florida Health Medical Oncology - Davis Cancer Pavilion

Gainesville, Florida, 32610, United States
University of Iowa Hospitals and Clinics

Iowa City, Iowa, 52242, United States
University of Massachusetts Worcester

Worcester, Massachusetts, 01655, United States
University of Texas Southwestern Medical Center

Dallas, Texas, 75390, United States
Universitätsklinik Ulm - Oberen Eselsberg

Ulm, Tübingen, 89081, Germany
Velindre University NHS Trust

Cardiff, CF14 2TL, United Kingdom

Conditions

Explore the condition pages connected to this study.

COLORECTAL ADENOCARCINOMA COLORECTAL CANCER COLORECTAL CANCER METASTATIC COLORECTAL NEOPLASMS NEOPLASM, COLORECTAL