Simple blood, breath, and stool tests could revolutionize colon cancer screening

NCT ID NCT06515821

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is testing new, easy-to-use screening tools for colorectal cancer (CRC) in over 4,000 adults across Europe. Participants provide blood, breath, stool, and cheek swab samples, which are analyzed for biomarkers, genetic risks, and chemical patterns. The goal is to develop low-cost, accurate tests that could detect CRC earlier than current methods, potentially making screening more accessible.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to simple, low-cost screening tests that catch colorectal cancer earlier, potentially saving lives through earlier treatment.
What could go wrong
This is an observational study, not a treatment trial. The new tests may not prove accurate enough to replace current methods like colonoscopy. Results are still years away from routine use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • IBO: Institutul Oncologic Prof. Dr. Alexandru Trestioreanu București

    NOT_YET_RECRUITING

    Bucharest, Romania

  • IPO: Instituto Português de Oncologia

    RECRUITING

    Porto, 4200-072, Portugal

  • LSMU: Lithuanian University of Health Sciences Gastroenterology Department,

    RECRUITING

    Kaunas, 50161, Lithuania

  • MKI UKSH Lübeck

    RECRUITING

    Lübeck, 23538, Germany

  • Military Medical Academy Sofia, Gastroenterology Clinic, 3 Sveti Georgi Sofiiski str., Sofia 1606, Bulgaria

    RECRUITING

    Sofia, 1606, Bulgaria

  • UFC: Université de Franche-Comté Oncology department CHU Besançon

    NOT_YET_RECRUITING

    Besançon, 25030, France

  • UMC Mainz: University Medical Center Mainz

    RECRUITING

    Mainz-GE, 55131, Germany

  • University Specialised Hospital for Active Treatment of Oncology Departement of Gastroenterology.

    NOT_YET_RECRUITING

    Sofia, 1797, Bulgaria

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