Experimental pill targets Hard-to-Treat cancers in groundbreaking trial
NCT ID NCT06326411
Summary
This early-stage trial is testing a new oral medication called NST-628 for adults with advanced solid tumors that have specific genetic changes in a key cancer growth pathway. The study aims to find a safe and effective dose and see if the drug can shrink tumors in patients who have exhausted all standard treatment options. It will enroll about 230 participants across multiple cancer types, including melanoma, lung cancer, and glioma.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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Cabrini Health Limited
RECRUITINGMalvern, Victoria, 3144, Australia
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Cabrini Hospital
RECRUITINGMalvern, Victoria, 3144, Australia
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Columbia University Medical Center
RECRUITINGNew York, New York, 10032, United States
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Gallipoli Medical Research Centre- Greenslopes Private Hospital
RECRUITINGGreenslopes, Queensland, 120, Australia
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Laura & Isaac Perlmutter Cancer Center at NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Memorial Slone Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
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NEXT Oncology - Austin
RECRUITINGAustin, Texas, 78758, United States
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NEXT Oncology - Dallas
RECRUITINGDallas, Texas, 75039, United States
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NEXT Oncology - Virginia
RECRUITINGFairfax, Virginia, 22031, United States
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Roswell Park
RECRUITINGBuffalo, New York, 14263, United States
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SCRI Oncology Partners
RECRUITINGNashville, Tennessee, 37203, United States
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START Moutain Region
RECRUITINGWest Valley City, Utah, 84119, United States
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Sarah Cannon Research Institute at Health ONE
RECRUITINGDenver, Colorado, 80218, United States
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Scientia Clinical Research, Ltd
RECRUITINGRandwick, New South Wales, 2031, Australia
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Southern Oncology Research Unit
RECRUITINGAdelaide, South Australia, 5042, Australia
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The Kinghorn Cancer Center, St. Vincent's Health Network
RECRUITINGDarlinghurst, New South Wales, 2010, Australia
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UCLA Hematology/Oncology
RECRUITINGWestwood, Los Angeles, California, 90024, United States
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UCSF Helen Diller Family Comprehensive Cancer Center
RECRUITINGSan Francisco, California, 94158, United States
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UPMC Hillman Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
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Vanderbilt-Ingram Cancer Center
RECRUITINGNashville, Tennessee, 37232, United States
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Yale Cancer Center
RECRUITINGNew Haven, Connecticut, 06511, United States
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Conditions
Explore the condition pages connected to this study.