First human test of targeted drug for Tough-to-Treat cancers

NCT ID NCT06533059

Recruiting now Disease control Sponsor: Alterome Therapeutics, Inc. Source: ClinicalTrials.gov ↗

Summary

This early-stage trial is testing a new oral drug called ALTA2618 for people with advanced cancers that have a specific genetic mutation called AKT1 E17K. The study aims to find the safest and most effective dose and see how well the drug works against cancers like breast and endometrial cancer that have spread and stopped responding to standard treatments. Researchers will enroll about 110 adults who have already tried other appropriate therapies.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

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La Jolla, California, 92093, United States
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Los Angeles, California, 90095, United States
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Denver, Colorado, 80218, United States
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Sarasota, Florida, 34232, United States
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Atlanta, Georgia, 30322, United States
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Boston, Massachusetts, 02114, United States
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Boston, Massachusetts, 02215, United States
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St Louis, Missouri, 63110, United States
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Mineola, New York, 11501, United States
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New York, New York, 10016, United States
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Maumee, Ohio, 43637, United States
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Nashville, Tennessee, 37203, United States
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WITHDRAWN

Dallas, Texas, 75230, United States
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Houston, Texas, 77030, United States
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San Antonio, Texas, 78229, United States
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Fairfax, Virginia, 22031, United States
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Madison, Wisconsin, 53792, United States
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Blacktown, New South Wales, 2148, Australia
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Randwick, New South Wales, 2031, Australia
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South Brisbane, Queensland, 4101, Australia
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Malvern, Victoria, 3144, Australia
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Nedlands, Western Australia, 6009, Australia
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Caen, 14000, France
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Dijon, 21000, France
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Saint-Herblain, 44805, France
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Villejuif, 94800, France
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Kyoto, 606-8507, Japan
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Matsuyama, 791-0280, Japan
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Shizuoka, 411-8777, Japan
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Tokyo, 135-8550, Japan
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Seoul, 03722, South Korea
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Seoul, 05505, South Korea
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Seoul, 06351, South Korea
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Seoul, 06591, South Korea
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Seoul, 13620, South Korea
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Barcelona, 08023, Spain
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Barcelona, 08035, Spain
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Barcelona, 08908, Spain
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Madrid, 28023, Spain
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Madrid, 28040, Spain
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Valencia, 46010, Spain
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Changhua, 500, Taiwan
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Taipei, 100, Taiwan
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Taipei, 10449, Taiwan
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London, SW3 6JJ, United Kingdom
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London, W1G 6AD, United Kingdom
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London, W1T 7HA, United Kingdom
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Manchester, M10 4BX, United Kingdom
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Newcastle upon Tyne, NE7 7DN, United Kingdom
Research Site
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Sutton, SM2 5PT, United Kingdom
Research Site #2
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San Antonio, Texas, 78229, United States

Conditions

Explore the condition pages connected to this study.

ADVANCED SOLID TUMOR BREAST CANCER CANCER ENDOMETRIAL CANCER METASTATIC CANCER