Brain injection method could revolutionize meningitis treatment

NCT ID NCT07495150

Not yet recruiting Disease control Sponsor: yilong Wang Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new method of giving antibiotics for moderate-to-severe bacterial meningitis. Instead of only giving antibiotics through a vein, doctors will also inject them into the skull bone to help more medicine reach the brain. The goal is to improve recovery in 86 adults who have not responded well to standard treatment.

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Conditions

The condition(s) this trial relates to.

bacterial meningitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BACTERIAL MENINGITIS BLOOD-BRAIN BARRIER

Contacts and locations

Locations

Beijing Tiantan Hospital

Beijing, Beijing Municipality, 100071, China
Henan Provincial People's Hospital

Zhengzhou, Henan, 450000, China
Kaifeng Central Hospital

Kaifeng, Henan, China
Linyi City People Hospital

Linyi, Shandong, China
The First Affiliated Hospital of Xinxiang Medical University

Xinxiang, Henan, China
Tianjin Huanhu Hospital

Tianjin, Tianjin Municipality, 300000, China

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Other studies related to the condition(s) this trial covers.