Gel could restore sensation in transgender surgery
NCT ID NCT05897086
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a gel made from polyethylene glycol (PEG) can help nerves heal better after phalloplasty, a surgery that creates a penis for transgender men. Currently, many patients lose sensation in the new organ, causing distress. The gel is applied during surgery to fuse nerve ends and may improve touch and sexual feeling. Thirty adults will be enrolled to see if the treatment leads to better sensory recovery and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Polyethylene Glycol 3350 (PEG) applied as a topical irrigation solution
What this could lead to
If it works, this could improve sensation and sexual function after phalloplasty, reducing regret and improving quality of life for transgender men.
What could go wrong
This is an early combined Phase 2/3 trial with only 30 participants, so results may not apply broadly. The gel is new for this use, and nerve healing is complex.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for GENDER DYSPHORIA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States