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Heel pain Face-Off: nerve zapping vs. Blood-Based injection vs. both

NCT ID NCT07826234

Symptom relief Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time

Summary

Plantar fasciitis causes heel pain when the tissue supporting the foot arch degenerates. Standard treatments like physical therapy, anti-inflammatory drugs, and orthotics help most people, but some continue to have pain for months. Researchers are testing three ultrasound-guided procedures: pulsed radiofrequency to calm a foot nerve, platelet-rich plasma injections to stimulate tissue repair, or both together. The trial will enroll 75 adults with persistent heel pain and follow them for six months to measure pain, function, and safety.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
pulsed radiofrequency to Baxter's nerve, platelet-rich plasma injection, or both together
What this could lead to
If one approach works better, doctors could have a clearer way to treat stubborn heel pain that has not improved with standard care.
What could go wrong
This is a small, single-center study with 75 people, so results may not apply to everyone. Procedures carry small risks like infection, bleeding, or nerve irritation, and some people may not get lasting relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 75 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 to 65 years. * Clinical diagnosis of recalcitrant plantar fasciitis with symptoms persisting for more than 6 months despite conservative treatment. * Failure of conventional non-surgical therapy (including activity modification, NSAIDs, stretching exercises, physiotherapy, and foot orthoses) for at least 3 months. * Morning heel pain localized to the medial calcaneal tubercle. * Local tenderness upon palpation over the medial calcaneal tubercle. * Plantar fascia thickness greater than 4 mm confirmed by musculoskeletal ultrasound. * Ability to understand the study protocol and provide written informed consent. Exclusion Criteria: * Previous surgical intervention for plantar fasciitis * Previous radiofrequency ablation or neuromodulation around the foot or ankle * Platelet-rich plasma (PRP) injection within the previous 6 months * Local corticosteroid injection within the previous 3 months * Evidence of calcaneal stress fracture * Coexisting tarsal tunnel syndrome or history of Baxter's nerve surgery * Systemic inflammatory arthritis (e.g., rheumatoid arthritis, ankylosing spondylitis, reactive arthritis) * Pregnancy * Active local (foot/ankle) or systemic infection * Coagulopathy, bleeding disorders, or ongoing anticoagulant therapy that cannot be safely interruptedMalignancy or severe psychiatric illness * Malignancy or severe psychiatric illness * Inability or refusal to provide informed consent

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Conditions

The condition(s) this trial relates to.

nerve compression syndrome plantar fasciitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Heel pain Nerve compression syndromes Plantar fasciitis

How to take part

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  1. The official record

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