New pain block technique could slash opioid use after jaw surgery

NCT ID NCT05351151

Completed Symptom relief Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether ultrasound-guided nerve blocks in the jaw could reduce pain and opioid use after maxillomandibular osteotomy (jaw realignment surgery). Fifty patients aged 15 to 45 were enrolled. One group received nerve blocks with ropivacaine, while the other had standard lidocaine injections at incision sites. The main goal was to measure opioid consumption in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ropivacaine and Lidocaine (local anesthetics)
What this could lead to: If effective, this approach could reduce the need for strong painkillers like opioids after jaw surgery, leading to fewer side effects and faster recovery.
What could go wrong: This is a small, completed study with only 50 participants. The results may not apply to all patients or surgeries, and nerve blocks carry risks like infection or nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PAIN POST OPERATIVE REGIONAL ANESTHESIA

Contacts and locations

Locations

University Hospital of Toulouse

Toulouse, 31100, France

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