Nerve block before bypass may stop post-surgery heart flutter
NCT ID NCT07570940
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a numbing injection around a nerve cluster in the neck, given just before heart bypass surgery, can prevent a common complication called atrial fibrillation (irregular heartbeat) in the first week after surgery. About 450 adults scheduled for bypass will be randomly assigned to receive either the numbing drug (liposomal bupivacaine) or a placebo (salt water) injection. Their heart rhythms will be monitored continuously with a wearable ECG device.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
liposomal bupivacaine
What this could lead to
If it works, this could provide a simple, non-drug way to prevent a common and serious heart rhythm problem after bypass surgery.
What could go wrong
This is a single, early-phase 4 trial at one center. The nerve block may not reduce AFib risk, and there are risks from the injection itself, such as bleeding or nerve damage.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States