Can a smart armband take the sting out of migraine shots?
NCT ID NCT05730556
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a wearable armband called Nerivio that uses mild electrical pulses to reduce pain from Botox injections in people with chronic migraine. About 80 participants were planned, but the study was stopped early. The goal was to see if the device could make the injection process less painful.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Nerivio (remote electrical neuromodulation device)
- What this could lead to
- If it worked, this device could offer a drug-free way to reduce pain during migraine injection procedures.
- What could go wrong
- The study was terminated early, so we have little data. It was also small (80 people) and only looked at short-term pain relief during injections.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mayo Clinic in Arizona
Scottsdale, Arizona, 85259, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a No-Fridge migraine shot replace botox?
- Could a common cholesterol drug stop chronic migraine?
- Migraine relief may sharpen the mind: study investigates cognitive benefits of preventive therapies
- New combo therapy for chronic migraine: atogepant plus botox under study
- Thousands to test new migraine meds in largest Real-Life study