New drug aims to shrink hard-to-treat tumors
NCT ID NCT07612189
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests an experimental drug called NEOK002 in people with advanced solid tumors that have spread and cannot be removed by surgery. The drug is designed to target two proteins on cancer cells to deliver a toxic payload. The study has two parts: first, finding the safest dose, and then, checking if the drug can shrink tumors. About 155 participants will take part.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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MD Anderson Cancer Center
NOT_YET_RECRUITINGHouston, Texas, 77030, United States
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Memorial Sloan Kettering Cancer Center
NOT_YET_RECRUITINGNew York, New York, 10065, United States
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NEXT Oncology
NOT_YET_RECRUITINGAustin, Texas, 78758, United States
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NEXT Oncology
NOT_YET_RECRUITINGDallas, Texas, 78299, United States
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NEXT Oncology
NOT_YET_RECRUITINGHouston, Texas, 77054, United States
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NEXT Oncology
RECRUITINGSan Antonio, Texas, 75039, United States
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NEXT Oncology
NOT_YET_RECRUITINGFairfax, Virginia, 22031, United States
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SCRI Oncology Partners
NOT_YET_RECRUITINGNashville, Tennessee, 37203, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New drug targets Hard-to-Treat cancers by homing in on a specific protein
- New drug combo aims to tackle Hard-to-Treat HER2 cancers
- New drug NEOK001 targets Hard-to-Treat cancers in first human trial
- New drug IBI133 tested in 19 patients with Hard-to-Treat cancers
- New drug IBI343 takes on advanced cancers in first human trial