New drug IBI343 takes on advanced cancers in first human trial

NCT ID NCT05458219

Recruiting now Disease control Sponsor: Innovent Biologics (Suzhou) Co. Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests a new drug called IBI343 in people with advanced solid tumors that cannot be removed by surgery or have spread. The main goals are to check safety, find the best dose, and see if the drug can shrink tumors. About 470 participants will take part in multiple countries.

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Conditions

The condition(s) this trial relates to.

biliary tract cancer gastroesophageal junction adenocarcinoma metastatic malignant neoplasm pancreatic ductal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOCALLY ADVANCED UNRESECTABLE OR METASTATIC SOLID TUMORS

Contacts and locations

Locations

Anhui Cancer Hospital
RECRUITING

Hefei, Anhui, China
Anhui Provincial Hospital
RECRUITING

Hefei, Anhui, China
Beijing Cancer Hospital
RECRUITING

Beijing, Beijing Municipality, China
Cancer Care Wollongong
RECRUITING

Wollongong, New South Wales, 2500, Australia
Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, Shanghai Municipality, China
Fujian Cancer Hospital
RECRUITING

Fuzhou, Fujian, China
Henan Provincial People's Hospital
RECRUITING

Zhengzhou, Henan, China
Hubei Cancer Hospital
RECRUITING

Wuhan, Hubei, China
Hunan Cancer Hospital
RECRUITING

Changsha, Hunan, China
Jiangxi Cancer Hospital
RECRUITING

Nanchang, Jiangxi, China
Jinan Central Hospital
RECRUITING

Jinan, Shandong, China
Jining First People's Hospital
RECRUITING

Jining, Shandong, China
Nanjing Drum Tower Hospital
RECRUITING

Nanjing, Jiangsu, China
Next Oncology-Austin
RECRUITING

Austin, Texas, 78758, United States
Next Oncology-Dallas
RECRUITING

Irving, Texas, 75039, United States
Next Oncology-San Antonio
RECRUITING

San Antonio, Texas, 78229, United States
Ningbo Medical Center Li Huili Hospital
RECRUITING

Ningbo, Zhejiang, China
Ningxia Medical University General Hospital
RECRUITING

Yinchuan, Ningxia, China
Pindara Private Hospital
ACTIVE_NOT_RECRUITING

Benowa, Queensland, 4217, Australia
Renji Hospital, Shanghai Jiaotong University School of Medicine
RECRUITING

Shanghai, Shanghai Municipality, China
Ruijin Hospital, Shanghai Jiaotong University School of Medicine
RECRUITING

Shanghai, Shanghai Municipality, China
Shandong Cancer Hospital
RECRUITING

Jinan, Shandong, China
St Vincent's Hospital Sydney
RECRUITING

Darlinghurst, New South Wales, 2010, Australia
Sun Yat-sen Memorial Hospital Sun Yat-Sen university
RECRUITING

Guangzhou, Guangzhou, China
Sunshine Coast University Private Hospital
RECRUITING

Birtinya, Queensland, 4575, Australia
The Affiliated Hospital of Qingdao University
RECRUITING

Qingdao, Shandong, China
The First Affiliated Hospital of Sun Yat-sen University
RECRUITING

Guangzhou, Guangzhou, China
The First Affiliated Hospital of Wannan Medical College
RECRUITING

Wuhu, Anhui, China
The First Affiliated Hospital of Xi'an Jiaotong University
RECRUITING

Xi'an, Shaanxi, China
The First Affiliated Hospital of Zhengzhou University
RECRUITING

Zhengzhou, Henan, China
The First Affiliated Hospital, Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, China
The First Hospital of China Medical University
RECRUITING

Shenyang, Liaoning, China
The Second Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, Jiangxi, China
Tianjin Cancer Hospital
RECRUITING

Tianjin, Tianjin Municipality, China
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technolog
RECRUITING

Wuhan, Hubei, China
Tumor Hospital, Chinese Academy of Medical Sciences
RECRUITING

Beijing, Beijing Municipality, China
West China Hospital of Sichuan University
RECRUITING

Chengdu, Sichuan, China
Zhejiang Cancer Hospital
RECRUITING

Hangzhou, Zhejiang, China
Zhejiang Provincial People's Hospital
RECRUITING

Hangzhou, Zhejiang, China

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