New drug IBI343 takes on advanced cancers in first human trial
NCT ID NCT05458219
First seen Nov 10, 2025 · Last updated Jun 16, 2026 · Updated 38 times
Summary
This early-phase study tests a new drug called IBI343 in people with advanced solid tumors that cannot be removed by surgery or have spread. The main goals are to check safety, find the best dose, and see if the drug can shrink tumors. About 470 participants will take part in multiple countries.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Anhui Cancer Hospital
RECRUITINGHefei, Anhui, China
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Anhui Provincial Hospital
RECRUITINGHefei, Anhui, China
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Beijing Cancer Hospital
RECRUITINGBeijing, Beijing Municipality, China
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Cancer Care Wollongong
RECRUITINGWollongong, New South Wales, 2500, Australia
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Fudan University Shanghai Cancer Center
RECRUITINGShanghai, Shanghai Municipality, China
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Fujian Cancer Hospital
RECRUITINGFuzhou, Fujian, China
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Henan Provincial People's Hospital
RECRUITINGZhengzhou, Henan, China
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Hubei Cancer Hospital
RECRUITINGWuhan, Hubei, China
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Hunan Cancer Hospital
RECRUITINGChangsha, Hunan, China
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Contact
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Jiangxi Cancer Hospital
RECRUITINGNanchang, Jiangxi, China
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Jinan Central Hospital
RECRUITINGJinan, Shandong, China
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Jining First People's Hospital
RECRUITINGJining, Shandong, China
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Nanjing Drum Tower Hospital
RECRUITINGNanjing, Jiangsu, China
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Next Oncology-Austin
RECRUITINGAustin, Texas, 78758, United States
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Next Oncology-Dallas
RECRUITINGIrving, Texas, 75039, United States
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Next Oncology-San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
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Ningbo Medical Center Li Huili Hospital
RECRUITINGNingbo, Zhejiang, China
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Ningxia Medical University General Hospital
RECRUITINGYinchuan, Ningxia, China
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Pindara Private Hospital
ACTIVE_NOT_RECRUITINGBenowa, Queensland, 4217, Australia
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Renji Hospital, Shanghai Jiaotong University School of Medicine
RECRUITINGShanghai, Shanghai Municipality, China
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Ruijin Hospital, Shanghai Jiaotong University School of Medicine
RECRUITINGShanghai, Shanghai Municipality, China
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Shandong Cancer Hospital
RECRUITINGJinan, Shandong, China
Contact
Contact
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St Vincent's Hospital Sydney
RECRUITINGDarlinghurst, New South Wales, 2010, Australia
Contact Email: •••••@•••••
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Sun Yat-sen Memorial Hospital Sun Yat-Sen university
RECRUITINGGuangzhou, Guangzhou, China
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Sunshine Coast University Private Hospital
RECRUITINGBirtinya, Queensland, 4575, Australia
Contact Email: •••••@•••••
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The Affiliated Hospital of Qingdao University
RECRUITINGQingdao, Shandong, China
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The First Affiliated Hospital of Sun Yat-sen University
RECRUITINGGuangzhou, Guangzhou, China
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The First Affiliated Hospital of Wannan Medical College
RECRUITINGWuhu, Anhui, China
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The First Affiliated Hospital of Xi'an Jiaotong University
RECRUITINGXi'an, Shaanxi, China
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The First Affiliated Hospital of Zhengzhou University
RECRUITINGZhengzhou, Henan, China
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The First Affiliated Hospital, Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, China
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The First Hospital of China Medical University
RECRUITINGShenyang, Liaoning, China
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The Second Affiliated Hospital of Nanchang University
RECRUITINGNanchang, Jiangxi, China
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Tianjin Cancer Hospital
RECRUITINGTianjin, Tianjin Municipality, China
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Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technolog
RECRUITINGWuhan, Hubei, China
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Tumor Hospital, Chinese Academy of Medical Sciences
RECRUITINGBeijing, Beijing Municipality, China
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West China Hospital of Sichuan University
RECRUITINGChengdu, Sichuan, China
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Zhejiang Cancer Hospital
RECRUITINGHangzhou, Zhejiang, China
Contact
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Zhejiang Provincial People's Hospital
RECRUITINGHangzhou, Zhejiang, China
Contact
Conditions
Explore the condition pages connected to this study.
Conditions inferred from the trial description
These were inferred from the trial's summary, not listed by the trial registrant.