Could a fentanyl spray replace needles for emergency pain?
NCT ID NCT06281951
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage study tests two ways to give fentanyl without needles: a face mask and a nasal spray. Twenty healthy volunteers will receive small doses to see how well the drug enters the body. The goal is to find a faster, easier way to manage pain in emergency rooms without needing an IV.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
fentanyl
What this could lead to
If successful, this could point toward a needle-free way to deliver fast pain relief in emergency rooms.
What could go wrong
This is a very early, small study in healthy people, not patients in pain. It only measures how the drug moves through the body, not whether it actually relieves pain effectively.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University Hospital, Rouen
RECRUITINGRouen, France, 76031, France