Could a fentanyl spray replace needles for emergency pain?
NCT ID NCT06281951
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage study tests two ways to give fentanyl without needles: a face mask and a nasal spray. Twenty healthy volunteers will receive small doses to see how well the drug enters the body. The goal is to find a faster, easier way to manage pain in emergency rooms without needing an IV.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fentanyl
- What this could lead to
- If successful, this could point toward a needle-free way to deliver fast pain relief in emergency rooms.
- What could go wrong
- This is a very early, small study in healthy people, not patients in pain. It only measures how the drug moves through the body, not whether it actually relieves pain effectively.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Hospital, Rouen
RECRUITINGRouen, France, 76031, France
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