Inhaled antibiotics aim to beat pneumonia in ECMO patients
NCT ID NCT06602557
First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time
Summary
This study investigates whether inhaling the antibiotic amikacin can better treat pneumonia caused by gram-negative bacteria in patients on veno-arterial ECMO (a heart-lung bypass machine). Standard antibiotics often fail in these patients, possibly because the bypass reduces blood flow to the lungs, limiting drug delivery. The trial compares inhaled amikacin plus standard care versus standard care alone, measuring bacterial clearance after five days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Amikacin (inhaled)
- What this could lead to
- If it works, this could offer a new way to treat pneumonia in critically ill patients on ECMO, potentially reducing treatment failure.
- What could go wrong
- This is a small early-phase trial, so results may not apply broadly. Inhaled antibiotics can cause airway irritation or bronchospasm, and the drug may not reach infected areas effectively.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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