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Laser treatment fails to improve root canal outcomes in small study

NCT ID NCT07243353

Completed Knowledge-focused Sponsor: Kırıkkale University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether using a special laser (Nd:YAG) during root canal treatment could help reduce inflammation and oxidative stress in infected teeth. Researchers measured certain markers in fluid samples from 58 patients. The results showed that the laser did not provide any extra benefit compared to standard root canal treatment alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Nd:YAG laser
What this could lead to
If successful, this approach might have pointed toward a new way to improve root canal outcomes by reducing inflammation.
What could go wrong
The trial was small (58 patients) and already completed with negative results—the laser showed no advantage over standard treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic apical periodontitis periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

APICAL PERIODONTITIS APICAL PERIODONTITIS OXIDATIVE STRESS OXIDATIVE STRESS

Contacts and locations

Locations

  • Kırıkkale Üniversitesi Diş Hekimliği Fakültesi

    Kirikkale, Turkey (Türkiye)

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