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Can Antioxidant-Rich foods counteract air Pollution's harmful effects?

NCT ID NCT07797413

Prevention Sponsor: Georgia Southern University Source: ClinicalTrials.gov ↗

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Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Expanded access (paused)
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Sep 01, 2026 · Last updated Sep 02, 2026 · Updated 1 time

Summary

This pilot study tests whether eating foods naturally rich in antioxidants and anti-inflammatory nutrients can reduce the harmful effects of air pollution in adults living near the Port of Savannah. Participants will either receive biweekly grocery deliveries of these foods or continue their usual diet. Researchers will measure markers of airway inflammation, oxidative stress, and cardiometabolic health, along with indoor air pollution levels. The goal is to see if this dietary approach is feasible and whether it may help protect against pollution-related health risks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Antioxidant- and nutrient-rich food-based nutrition intervention (biweekly grocery deliveries of foods high in vitamins C and E, omega-3 fatty acids, and polyphenols)
What this could lead to
If this approach works, it could point toward a practical, food-based way to help people in polluted areas reduce airway inflammation and oxidative stress, potentially lowering their risk of related health problems.
What could go wrong
This is a small pilot study with only 20 participants, so the results may not apply broadly. The diet may not produce measurable changes, and the study is designed mainly to test feasibility, not to prove effectiveness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Residing in Port Wentworth or the Savannah main Channel at a 3-mile radius for the prior 12 months and not planning to move during the study. * Non-smoking status (or specified ANY smoking history) * Absence of pre-existing chronic respiratory conditions (Asthma, Chronic Obstructive Pulmonary Disease, Seasonal respiratory allergies that require the use of antihistamines or immunosuppressants more than once a month, Chronic Bronchitis, and Heart Failure or any condition that would put participants at a greater risk than other participants for a pre-existing condition. * Willingness and ability to participate in home monitoring protocols * Willingness to receive and use grocery delivery for the nutrition intervention * Willingness and ability to follow the study procedures * Own a refrigerator * Allow investigators to do 1.5 hour home visits, and several calls and texts * Having a kitchen and the ability to prepare, cook meals, and eat them at home * Living in a household with 4 or fewer people Exclusion Criteria: * Individuals unable to follow study procedures * Antihistamines or any immunosuppressors, ongoing cancer treatment or within the past 5 years * Individuals unable to read, speak, and/or understand English or Spanish * Any food allergy * Strong dislike to most vegetables or fruits * Having ever been diagnosed with an eating disorder or autoimmune disorder * Being currently treated for any type of cancer * Households with 5 or more people living in the same space

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Air pollution exposure Airway inflammation Oxidative stress

How to take part

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  1. The places running it

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  2. The official record

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Contacts and locations

Locations

  • Georgia Southern University and GROW Initiative GA

    Savannah, Georgia, 31419, United States

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