Liver disease study aims to unlock secrets of weight loss surgery
NCT ID NCT04141592
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares people with non-alcoholic fatty liver disease (NAFLD) to healthy controls to understand how the immune system, metabolism, and gut bacteria differ. Researchers will also track what happens to liver health in NAFLD patients who undergo weight loss surgery. The goal is to learn why some patients improve after surgery and identify markers that could guide future treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Bariatric surgery (weight loss surgery)
What this could lead to
If successful, this could reveal key biological pathways in NAFLD and show whether weight loss surgery can reverse liver damage.
What could go wrong
This is an observational study, not a treatment trial. Results may not lead to new therapies, and findings may not apply to all NAFLD patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Homerton University Hospital Foundation Trust
RECRUITINGLondon, Greater London, E9 6SR, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••