Ear cartilage injection may offer longer knee pain relief than PRP
NCT ID NCT07453953
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial tests whether a single injection of Mytocel MSK (made from a patient's own ear cartilage) can improve knee osteoarthritis better than standard PRP injections. Thirty adults with mild-to-moderate knee arthritis will receive either the new cell therapy or PRP. Researchers will track pain, function, and cartilage changes over 52 weeks using questionnaires and MRI scans.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Mytocel MSK with AMT (autologous micrograft from ear cartilage)
What this could lead to
If it works, this could offer a longer-lasting, single-injection treatment for knee osteoarthritis, reducing pain and improving joint function.
What could go wrong
This is a very early (Phase 1) trial with only 30 participants, so results may not be generalizable. The procedure involves harvesting ear cartilage, which carries minor surgical risks.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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