MS mystery: do some relapses hide from MRI scans?

NCT ID NCT07545889

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether people with relapsing-remitting multiple sclerosis (RRMS) can have a relapse—new or worsening symptoms—without any visible inflammation on an MRI scan. Researchers will follow 136 adults who are having a suspected relapse, performing early brain and spinal MRIs to check for active lesions. The goal is to better understand these 'invisible' relapses, improve diagnosis, and avoid unnecessary treatments. Participants will also have follow-up visits at 6 months to track their recovery and quality of life.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Dijon Bourgogne

    Dijon, 21079, France

  • CHU de Nancy

    Nancy, 54035, France

  • Centre Hospitalier de Haguenau

    Haguenau, 67504, France

  • Chr Metz-Thionville

    Metz, 57085, France

  • Chu Reims

    Reims, 51092, France

  • Grpe Hosp Region Mulhouse & Sud Alsace

    Mulhouse, 68051, France

  • Hospices Civils de Colmar

    Colmar, 68024, France

  • Hôpitaux Universitaires de Strasbourg

    Strasbourg, 67098, France

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