PCOS fertility boost? supplement myo-inositol tested in major trial
NCT ID NCT03059173
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests whether adding myo-inositol (a natural supplement) to standard clomiphene citrate treatment helps women with polycystic ovary syndrome (PCOS) ovulate more successfully. 276 women who want to become pregnant will be randomly assigned to receive either the supplement or a placebo, alongside their fertility medication. The goal is to see if the supplement reduces the number of women who do not ovulate at all during treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
myo-inositol and levomefolic acid (dietary supplement) plus clomiphene citrate (drug)
What this could lead to
If it works, this could offer a simple, low-cost supplement to help women with PCOS ovulate and become pregnant with fewer failed cycles.
What could go wrong
This is a phase 3 trial, but the supplement may not improve ovulation rates. Results may not apply to all PCOS patients, and side effects from clomiphene citrate are possible.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU de Lille hôpital Jeanne de Flandre
RECRUITINGLille, France
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