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Stem cell transplant vs. drugs: which works better for younger myeloma patients?

NCT ID NCT01191060

Completed Disease control Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 700 adults up to age 65 with multiple myeloma to see if high-dose therapy with a stem cell transplant works better than standard drug therapy (lenalidomide, bortezomib, and dexamethasone). The goal was to find out which approach delays the cancer from growing longer. Participants were randomly assigned to one of the two treatments and followed for up to 4 years.

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Conditions

The condition(s) this trial relates to.

Disease Progression plasma cell myeloma plasma cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MYELOMA

Contacts and locations

Locations

  • CH Bretagne Atlantique Vannes et Auray

    Vannes, 56017, France

  • CH Chambéry

    Chambéry, 73011, France

  • CH Louis Pasteur - Colmar

    Colmar, 68024, France

  • CH Meaux

    Meaux, 77104, France

  • CH René Dubos

    Cergy-Pontoise, 95303, France

  • CH Saint Jean

    Perpignan, 66046, France

  • CH Sud Francilien

    Corbeil-Essonnes, 91106, France

  • CH de Chartres - Hôpital Louis Pasteur

    Le Coudray, 26630, France

  • CH du Pays D'Aix

    Aix-en-Provence, 13 616, France

  • CHRU - Hôpital Bretonneau

    Tours, 37044, France

  • CHRU - Hôpital Claude Huriez

    Lille, 59037, France

  • CHRU - Hôpital Jean Bernard

    Poitiers, 86021, France

  • CHRU - Hôpital Sud

    Rennes, 35056, France

  • CHRU - Hôpital Sud Amiens

    Amiens, 80054, France

  • CHRU - Hôpital de Pontchaillou

    Rennes, 35033, France

  • CHRU - Hôpital du Haut Lévêque

    Pessac, 33604, France

  • CHRU - Hôtel Dieu

    Nantes, 44093, France

  • CHRU Dijon

    Dijon, 21000, France

  • CHU - Hôpital Edouard Herriot

    Lyon, 69437, France

  • CHU Caen Côte de Nacre

    Caen, 14033, France

  • CHU Henri Mondor

    Créteil, 94 010, France

  • CHU d'Angers

    Angers, 49033, France

  • CHU d'Estaing

    Clermont-Ferrand, 63000, France

  • CHU de Limoges

    Limoges, 87042, France

  • Centre Catherine de Sienne

    Nantes, 44 202, France

  • Centre François Baclesse

    Caen, 14076, France

  • Centre Henri Becquerel

    Rouen, 76038, France

  • Centre Hospitalier Argenteuil Victor Dupouy

    Argenteuil, 95 100, France

  • Centre Hospitalier Départemental - La réunion St Denis

    Saint-Denis, 97 405, France

  • Centre Hospitalier Général - Dunkerque

    Dunkirk, 59 385, France

  • Centre Hospitalier H.Duffaut

    Avignon, 84902, France

  • Centre Hospitalier Lyon sud

    Pierre-Bénite, 69495, France

  • Centre Hospitalier William Morey

    Chalon-sur-Saône, 71 321, France

  • Centre Hospitalier Yves le Foll

    Saint-Brieuc, 22 027, France

  • Centre Hospitalier de Blois

    Blois, 41016, France

  • Centre Hospitalier de Valence

    Valence, 26953, France

  • Centre Hospitalier de la côte basque

    Bayonne, 64109, France

  • Centre Hospitalier de la région d'Annecy

    Pringy, 74374, France

  • Centre Jean Bernard

    Le Mans, 72000, France

  • Centre Léon Bérard

    Lyon, France

  • Centre René Huguenin

    Saint-Cloud, 92210, France

  • Centre hospitalier Bodelio

    Lorient, 56322, France

  • Centre hospitalier Le Mans

    Le Mans, 72037, France

  • Centre hospitalier départemental - La Roche sur Yon cedex

    La Roche-sur-Yon, 85025, France

  • Groupe Hospitalier Sud Réunion

    Saint-Pierre, 97448, France

  • Groupe Hospitalo-Universitaire Carémeau

    Nîmes Cédex 9, 30029, France

  • Hopital E Muller

    Mulhouse, 68100, France

  • Hôpital A.Michallon

    Grenoble, 38043, France

  • Hôpital A.Morvan

    Brest, 29609, France

  • Hôpital Antoine Béclère

    Clamart, 92 141, France

  • Hôpital Archet 1

    Nice, 06202, France

  • Hôpital Avicenne

    Bobigny, 93009, France

  • Hôpital Cochin

    Paris, 75014, France

  • Hôpital Jean Minjoz

    Besançon, 25030, France

  • Hôpital R.Debré

    Reims, 51092, France

  • Hôpital Saint-Louis

    Paris, 75475, France

  • Hôpital St-Antoine

    Paris, 75571, France

  • Hôpital d'instruction des armées Percy

    Clamart, 92141, France

  • Hôpital de l'Archet

    Nice, 06202, France

  • Hôpitaux Universitaires de Strasbourg

    Strasbourg, 67091, France

  • Hôpitaux de Brabois

    Nancy, 54511, France

  • Institut Curie

    Paris, 75005, France

  • Institut Gustave Roussy

    Villejuif, 94 805, France

  • Institut Paoli Calmettes

    Marseille, 13273, France

  • Institut de Cancérologie de la Loire

    Saint-Priest-en-Jarez, 42 271, France

  • Pole Santé République

    Clermont-Ferrand, 63050, France

  • Polyclinique Bordeaux Nord Aquitaine

    Bordeaux, 33 300, France

  • University Hospital of Toulouse, Purpan

    Toulouse, 31059 Cedex 9, France

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