Scientists launch major study to unravel mysteries of rare lung infections

NCT ID NCT00018044

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to learn more about non-tuberculous mycobacterial (NTM) infections, which cause repeated lung and other organ infections. Researchers will study up to 1,000 participants to understand the genetics, symptoms, and best treatments for these infections. The study also compares NTM with similar conditions like Job syndrome and cystic fibrosis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Clofazimine

What this could lead to

If successful, this study could improve understanding of why some people get these infections and point toward better treatments.

What could go wrong

This is an observational study focused on collecting data, not testing a new cure. It may not lead to immediate treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cystic fibrosis hyper-IgE recurrent infection syndrome 1, autosomal dominant mycobacterial infectious disease Mycobacterium avium complex disease Mycobacterium Infections, Nontuberculous pulmonary non-tuberculous mycobacterial infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States