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Scientists launch major study to unravel mysteries of rare lung infections

NCT ID NCT00018044

Recruiting now Knowledge-focused Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 6 times

Summary

This study aims to learn more about non-tuberculous mycobacterial (NTM) infections, which cause repeated lung and other organ infections. Researchers will study up to 1,000 participants to understand the genetics, symptoms, and best treatments for these infections. The study also compares NTM with similar conditions like Job syndrome and cystic fibrosis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Clofazimine
What this could lead to
If successful, this study could improve understanding of why some people get these infections and point toward better treatments.
What could go wrong
This is an observational study focused on collecting data, not testing a new cure. It may not lead to immediate treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cystic fibrosis hyper-IgE recurrent infection syndrome 1, autosomal dominant mycobacterial infectious disease Mycobacterium avium complex disease Mycobacterium Infections, Nontuberculous pulmonary non-tuberculous mycobacterial infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MYCOBACTERIUM INFECTIONS

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.