Could a pill shield your brain during radiation?
NCT ID NCT05417282
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tested a drug called MW151 in 27 adults with brain tumors who were receiving whole-brain radiation. The drug aims to reduce brain inflammation and prevent memory and thinking problems that often follow radiation. The study focused on safety, but also looked for signs that the drug might help protect cognitive function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MW151 (a drug that reduces brain inflammation)
What this could lead to
If it works, this could point toward a way to protect memory and thinking skills in people who need brain radiation for cancer.
What could go wrong
This is a very early Phase 1 trial with only 27 people, so it is too small to prove effectiveness. The main goal was safety, not whether it actually prevents cognitive decline.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for COGNITIVE DYSFUNCTION, COGNITIVE DISORDER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Northwestern Memorial HealthCare, Central DuPage Hospital, Warrenville Cancer Center
Winfield, Illinois, 60555, United States