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New drug MTM-H-001 targets B-Cell autoimmune diseases in early trial

NCT ID NCT07593911

Not yet recruiting Disease control Sponsor: Beijing GoBroad Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study tests a new drug called MTM-H-001 in 75 adults with B-cell-related autoimmune diseases, including lupus, multiple sclerosis, and rheumatoid arthritis. The main goal is to check safety and find the right dose. Participants receive the drug by injection, and researchers will monitor side effects and any changes in disease activity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
MTM-H-001 injection
What this could lead to
If successful, this could point toward a new treatment option for several autoimmune diseases by targeting B-cells.
What could go wrong
This is a very early, small study (75 people) with no control group. It primarily checks safety and dosing, so it may not show clear benefit or could have unexpected side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Immunoglobulin G4-Related Disease immunoglobulin G4-related sclerosing disease lupus nephritis multiple sclerosis myasthenia gravis rheumatoid arthritis systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IGG4-RELATED DISEASES LUPUS NEPHRITIS (LN) MULTIPLE SCLEROSIS MYASTHENIA GRAVIS (MG) RHEUMATOID ARTHRITIS (RA) SYSTEMIC LUPUS ERTHEMATOSUS (SLE)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Beijing GoBroad Hospital

    Beijing, Beijing Municipality, 102206, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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