Immune cells Tailor-Made to attack pancreatic cancer enter first human test

NCT ID NCT06549751

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests a new therapy called MT-601, which uses a patient's own immune T-cells trained to recognize multiple cancer-related targets. It is for people with advanced pancreatic cancer that cannot be removed by surgery or has spread. The study will check safety and whether the cells can shrink tumors, with up to 38 participants receiving different doses alongside chemotherapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Patient-derived multi-tumor-associated antigen specific T cells (MT-601)

What this could lead to

If it works, this could point toward a new treatment option for advanced pancreatic cancer that uses a patient's own immune cells to fight the tumor.

What could go wrong

This is a very early Phase 1 trial with only 38 participants, so safety and effectiveness are not yet proven. The therapy may not shrink tumors or could cause serious side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Texas MD Anderson

    Houston, Texas, 77030, United States