New study aims to predict MS risk using genes and environment

NCT ID NCT01353547

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is trying to figure out what makes someone more likely to develop multiple sclerosis (MS). Researchers are looking at a mix of genetic, environmental, and immune factors in 5,000 people in the US, including relatives of MS patients and others at higher risk. The goal is to create a risk score that could one day help with early detection or prevention.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a risk score that helps identify people at higher risk for MS, potentially enabling earlier monitoring or prevention strategies.

What could go wrong

This is an observational study, not a treatment trial. It may not produce a usable risk algorithm, and results may not apply to the general population.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    TERMINATED

    Boston, Massachusetts, 02115, United States

  • Columbia University Irving Center

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Massachusetts General Hospital

    TERMINATED

    Boston, Massachusetts, 02114, United States

  • National Institute of Neurological Disorders and Stroke

    RECRUITING

    Bethesda, Maryland, 15213, United States

    Contact

  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact