New MRI trick may spot hidden brain tumors without a biopsy
NCT ID NCT04246879
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether an extra MRI scan, taken later than usual, can better tell the difference between a growing tumor and harmless radiation scar in people with brain metastases who have had radiosurgery. Twenty-five adults with solid tumors (except small cell lung cancer or lymphoma) will get the delayed MRI, and results will be checked against a biopsy. If it works, it could spare patients from unnecessary invasive procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could give doctors a more accurate way to tell whether a brain lesion is a returning tumor or harmless scar tissue, reducing unnecessary biopsies.
What could go wrong
This is a small, early study with only 25 participants. The MRI technique may not prove reliable enough for routine use, and results may not apply to all tumor types.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Duke University Health System
Durham, North Carolina, 27710, United States