New MRI technique may spot complete cancer response without surgery
NCT ID NCT05876026
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This observational study looked at whether a special MRI measurement called T1 relaxation time can accurately detect scar tissue (fibrosis) that indicates a complete response to chemotherapy and radiation in people with locally advanced rectal cancer. 44 participants received standard treatment and had MRI scans before and after. The goal is to see if this MRI method could one day help doctors know when the cancer is gone without needing a biopsy or surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a non-invasive MRI method to identify which patients have a complete response to treatment, potentially avoiding unnecessary surgery.
- What could go wrong
- This is a small observational study (44 participants) that only measures a biomarker, not a treatment. The MRI technique may not be accurate enough to replace current methods.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for LOCALLY ADVANCED RECTAL CARCINOMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Vejle Hospital
Vejle, Jylland, 7100, Denmark
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Rearranging the treatment timeline: could a new sequence of chemo and radiation spare rectal cancer patients from major surgery?
- Rectal cancer: could a 'Watch and Wait' strategy spare patients from major surgery?
- Dye-Free laser imaging could replace standard dye in colorectal surgery
- Could your own gut bacteria restore bowel control after cancer surgery?
- New drug combo aims to eliminate rectal tumors before surgery
- Giving cancer patients a say in genetic results may boost knowledge and satisfaction