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Could MRI replace CT for sharper cancer radiation planning?

NCT ID NCT04545957

Recruiting now Disease control Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This study investigates whether using magnetic resonance imaging (MRI) instead of standard CT scans to plan radiation therapy can improve treatment accuracy and reduce side effects. It enrolls adults with prostate, liver, or head and neck cancers who need radiation. Researchers will assess how often MRI-based planning is feasible and whether it leads to better quality of life and disease control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
MRI simulator and radiation therapy
What this could lead to
If successful, this approach could make radiation therapy more precise, potentially reducing side effects and improving quality of life for people with certain cancers.
What could go wrong
This is an early-phase feasibility study, so it is not designed to prove effectiveness. The benefits seen may not apply to all patients or cancer types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

adenocarcinoma head and neck cancer Head and Neck Neoplasms liver cancer Liver Neoplasms prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEAD AND NECK CANCER LIVER CANCER PROSTATE CANCER RECURRENT ADENOCARCINOMA

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Email: •••••@•••••

    Contact

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Email: •••••@•••••

    Contact

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