MRI-Guided radiation: a sharper aim for HPV cancers?
NCT ID NCT03634267
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial tests whether using MRI scans to guide the placement of internal radiation (brachytherapy) can improve treatment for women with advanced cervical or vaginal cancers linked to HPV. The study involves 26 participants and compares MRI-guided placement to standard ultrasound or freehand methods. The goal is to see if MRI helps deliver a more precise radiation dose to the tumor while sparing nearby organs.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Internal radiation therapy (brachytherapy) guided by MRI
What this could lead to
If successful, this approach could make brachytherapy more precise, potentially improving tumor control and reducing side effects for women with cervical or vaginal cancer.
What could go wrong
This is a very early phase 1 trial with only 26 participants, so results may not apply to all patients. The technique requires MRI-compatible equipment and may not be feasible for everyone.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States