MRI-Guided radiation: a sharper aim for HPV cancers?
NCT ID NCT03634267
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial tests whether using MRI scans to guide the placement of internal radiation (brachytherapy) can improve treatment for women with advanced cervical or vaginal cancers linked to HPV. The study involves 26 participants and compares MRI-guided placement to standard ultrasound or freehand methods. The goal is to see if MRI helps deliver a more precise radiation dose to the tumor while sparing nearby organs.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Internal radiation therapy (brachytherapy) guided by MRI
- What this could lead to
- If successful, this approach could make brachytherapy more precise, potentially improving tumor control and reducing side effects for women with cervical or vaginal cancer.
- What could go wrong
- This is a very early phase 1 trial with only 26 participants, so results may not apply to all patients. The technique requires MRI-compatible equipment and may not be feasible for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
M D Anderson Cancer Center
Houston, Texas, 77030, United States
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