Can MRI reveal the hidden progression of muscular dystrophy?

NCT ID NCT01671865

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This study is looking at how magnetic resonance imaging (MRI) and spectroscopy can be used to detect and track changes in the muscles of people with facioscapulohumeral muscular dystrophy (FSHD). The goal is to identify reliable biomarkers—measurable indicators of disease activity—that could help in future research and clinical trials. Participants will undergo MRI scans and physical assessments, including muscle strength and timed function tests, to see how imaging findings relate to real-world muscle function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Magnetic resonance imaging and spectroscopy (non-invasive imaging techniques)
What this could lead to
If successful, this could establish reliable biomarkers to monitor disease progression and evaluate potential treatments in future clinical trials for FSHD.
What could go wrong
This is an observational study, so it won't directly test a treatment. The findings may not translate into immediate clinical benefits, and imaging changes may not perfectly correlate with muscle function.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Doris Leung

    Baltimore, Maryland, 21205, United States

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