Mpox vaccine immune response under the microscope in DRC

NCT ID NCT07499739

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 300 adults in the Democratic Republic of the Congo who received either the MVA-BN or LC16m8 mpox vaccine as part of a national campaign. Researchers collect blood samples at several time points to measure how well the vaccines trigger and maintain antibodies against the mpox virus. The goal is to understand the strength and duration of the immune response, which can help improve future vaccination efforts.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MVA-BN or LC16m8 mpox vaccine

What this could lead to

If successful, this study will clarify how well these vaccines trigger and maintain immunity against mpox, guiding future vaccination strategies.

What could go wrong

This is an observational study, not a treatment trial. Results may not apply to other populations, and immune response does not guarantee protection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

monkeypox prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Convivial Kasa-Vubu

    Kinshasa, Democratic Republic of the Congo

  • Kinoise

    Kinshasa, Democratic Republic of the Congo

  • Kokolo

    Kinshasa, Democratic Republic of the Congo