Massive mpox vaccine trial launches in DRC: could it stop the outbreak?

NCT ID NCT07093489

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This large study will test the LC16m8 mpox vaccine in nearly 12,000 people aged one year and older in the Democratic Republic of Congo. Researchers want to see if the vaccine can prevent mpox disease and monitor its safety. Participants will receive the vaccine as part of the government's rollout, and the study will compare infection rates between vaccinated and unvaccinated groups.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

LC16m8 mpox vaccine

What this could lead to

If successful, this could provide a safe and effective vaccine to protect against mpox in both children and adults.

What could go wrong

This is a real-world study, not a controlled lab trial, so results may be less clear. The vaccine may not reach the hoped-for 70% protection, and safety in young children or pregnant women is not yet known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

monkeypox prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Institut National de la Recherche Biomédicale (INRB)

    Kinshasa, Democratic Republic of the Congo

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact