Which opioid works best for day surgery pain? study pits morphine against hydromorphone
NCT ID NCT02223377
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two common opioids, morphine and hydromorphone, to see which provides better pain relief with less nausea and vomiting after same-day surgeries. About 400 adults undergoing procedures like gallbladder removal or hernia repair will receive one of the two drugs in the recovery room. The goal is to find the most effective option for managing pain while minimizing side effects, helping patients recover faster and more comfortably.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
morphine and hydromorphone
What this could lead to
If one drug proves clearly better, it could become the preferred choice for managing pain after day surgeries, improving patient comfort and recovery speed.
What could go wrong
This is a single study with 402 people, and results may not apply to all surgeries or patients. Both drugs can cause nausea, itching, or drowsiness.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hamilton Health Sciences
Hamilton, Ontario, L8L 2X2, Canada
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St. Joseph's Healthcare Hamilton
Hamilton, Ontario, L8N 4A6, Canada