New monkeypox vaccine enters human testing

NCT ID NCT06771479

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial is testing a new vaccine against monkeypox in 120 healthy adults aged 18 and older. Participants will receive two doses of either a low or high dose of the MVA strain live vaccine, or a placebo. The study aims to check if the vaccine is safe and whether it triggers an immune response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MVA strain monkeypox attenuated live vaccine

What this could lead to

If successful, this could lead to a safe and effective vaccine to prevent monkeypox infection.

What could go wrong

This is an early Phase 1 trial with only 120 participants, so safety and immune response are still being tested. The vaccine may not produce strong enough immunity or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

monkeypox prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Henan Infectious Disease Hospital

    RECRUITING

    Zhengzhou, Henan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••