Scientists grow mini lung tissue from blood to study severe asthma

NCT ID NCT05616338

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study took blood samples from 4 people with severe asthma or a related condition called ABPA. Researchers used the blood cells to create stem cells and then grew them into tiny models of bronchial tissue. The goal was to see if this lab-grown tissue could mimic real airways, helping scientists study mucus plugs and other features of severe asthma without needing invasive biopsies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this model could help researchers understand how mucus plugs form in severe asthma and ABPA, potentially pointing toward new treatments.

What could go wrong

This is a very early, small study with only 4 participants. It focuses on building a lab model, not testing a treatment, so it may not lead directly to patient benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

allergic bronchopulmonary aspergillosis asthma chronic asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • university Hospital of Montpellier

    Montpellier, 34295, France