Scientists grow mini lung tissue from blood to study severe asthma

NCT ID NCT05616338

Completed Knowledge-focused Sponsor: University Hospital, Montpellier Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study took blood samples from 4 people with severe asthma or a related condition called ABPA. Researchers used the blood cells to create stem cells and then grew them into tiny models of bronchial tissue. The goal was to see if this lab-grown tissue could mimic real airways, helping scientists study mucus plugs and other features of severe asthma without needing invasive biopsies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this model could help researchers understand how mucus plugs form in severe asthma and ABPA, potentially pointing toward new treatments.
What could go wrong: This is a very early, small study with only 4 participants. It focuses on building a lab model, not testing a treatment, so it may not lead directly to patient benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS (ABPA) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

allergic bronchopulmonary aspergillosis asthma chronic asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS (ABPA) SEVERE ASTHMA

Contacts and locations

Locations

university Hospital of Montpellier

Montpellier, 34295, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.