Computer-Guided drug dosing shows promise for diabetic patients with liver disease

This study tested whether using a computer model to adjust doses of two common drugs (sitagliptin for diabetes and duloxetine for nerve pain) works better in people with liver cirrhosis. 64 patients with cirrhosis, diabetes, and nerve pain were grouped by liver severity and given personalized doses. Researchers measured blood sugar control and pain relief, while monitoring side effects and liver/kidney function.