New drug targets rare genetic mutation in advanced cancers

NCT ID NCT06385496

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 27 times

Summary

This study tests a drug called MLN0128 (TAK-228) in 35 adults with advanced cancers (like lymphoma or solid tumors) that have a specific genetic change called an mTOR mutation. The drug works by blocking enzymes that cancer cells need to grow. The goal is to see if the drug can shrink tumors or stop them from growing. This is not a cure; it is a way to control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.