New catheter procedure tightens leaky heart valves without surgery

NCT ID NCT03929913

Completed Disease control Sponsor: National Heart, Lung, and Blood Institute (NHLBI) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tested a new, less invasive procedure to treat functional mitral regurgitation, a condition where a leaky heart valve causes heart failure symptoms like shortness of breath and fatigue. Nineteen adults with this condition received a permanently implanted device that tightens the valve like a purse-string, using catheters guided by X-ray and ultrasound, avoiding open-heart surgery. The goal was to see if the procedure could be done safely and effectively, with success measured immediately and at 30 days.

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Conditions

The condition(s) this trial relates to.

heart failure mitral valve insufficiency Ventricular Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FUNCTIONAL MITRAL REGURGITATION

Contacts and locations

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Locations

Carilion Medical Center

Roanoke, Virginia, 24014, United States
Emory University

Atlanta, Georgia, 30322-1102, United States
MedStar Washington Hospital Center

Washington D.C., District of Columbia, 20010, United States