Heart rhythm fix may also repair leaky valve: scientists build prediction model

NCT ID NCT07096219

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at people with persistent atrial fibrillation (an irregular heartbeat) and moderate-to-severe functional mitral regurgitation (a leaky heart valve). Researchers want to see if a procedure called catheter ablation—which zaps abnormal heart tissue to restore normal rhythm—can improve the valve leakage. They will also build and test a model to predict which patients are most likely to benefit. The goal is to help doctors make better treatment decisions for this common heart condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

catheter ablation

What this could lead to

If successful, this could help doctors predict which patients with atrial fibrillation and mitral regurgitation will benefit most from catheter ablation, enabling more personalized treatment decisions.

What could go wrong

This is an observational study, not a treatment trial. The predictive model may not be accurate enough for widespread use, and individual results can vary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

mitral valve insufficiency persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shantou Central Hospital

    Shantou, China

  • Sun Yat-sen Memorial Hospital of Sun Yat-sen University

    Guangzhou, Guangdong, 510000, China