MRI scans may predict who benefits from MitraClip heart valve repair

NCT ID NCT07131631

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will use cardiac MRI scans to measure heart muscle scarring in 125 people with heart failure and a leaky mitral valve who are scheduled for a MitraClip procedure. Researchers want to see if the amount of scarring predicts how well the heart recovers six months later. Participants will have an MRI before the procedure and again at six months, along with questionnaires about their symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors predict which patients will benefit most from the MitraClip procedure, leading to better treatment decisions.

What could go wrong

This is an observational study, not a treatment trial. It will not test a new therapy, and results may not change current practice immediately.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

heart failure mitral valve insufficiency systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cleveland Clinic

    ENROLLING_BY_INVITATION

    Cleveland, Ohio, 44195, United States

  • IRCCS Ospedale San Raffaele

    ENROLLING_BY_INVITATION

    Milan, 20132, Italy

  • Inova Fairfax Medical Campus

    ENROLLING_BY_INVITATION

    Falls Church, Virginia, 22042, United States

  • Minneapolis Heart Institute Foundation

    RECRUITING

    Minneapolis, Minnesota, 55407, United States

    Contact

    Contact Email: •••••@•••••

  • Sanger Heart and Vascular Institute

    ENROLLING_BY_INVITATION

    Charlotte, North Carolina, 28204, United States

  • The Christ Hospital Health Network

    ENROLLING_BY_INVITATION

    Cincinnati, Ohio, 45219, United States