Blue dye could make thyroid cancer surgery safer and more precise

NCT ID NCT07354698

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether injecting a blue dye called mitoxantrone hydrochloride into the thyroid during robotic surgery helps surgeons see and remove cancer-affected lymph nodes while avoiding the parathyroid glands. 114 people with papillary thyroid cancer will be randomly assigned to get the dye or not. The goal is to see if the dye reduces accidental removal of parathyroid glands and improves lymph node removal.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

mitoxantrone hydrochloride injection (a blue dye used as a lymphatic tracer)

What this could lead to

If it works, this dye could help surgeons remove more cancer-affected lymph nodes while sparing healthy parathyroid glands, reducing complications like low calcium levels.

What could go wrong

This is a small, early-phase trial (114 people) testing a dye, not a treatment. The dye may not improve outcomes, and there are risks from the surgery itself and possible allergic reactions to the dye.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Thyroid Cancer, Papillary thyroid gland papillary carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Daping Hospital

    Chongqicun, 400042, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••