New combo therapy could speed up kidney stone passage
NCT ID NCT07310797
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests two medications, mirabegron and tamsulosin, to see which works best for helping people pass ureteral stones and reducing pain. 500 adults with stones between 4-10 mm will be randomly assigned to one of four groups: mirabegron alone, tamsulosin alone, both drugs together, or standard care. The main goal is to see how many stones pass within 4 weeks, along with pain levels and side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Mirabegron and Tamsulosin
What this could lead to
If successful, this could show that mirabegron, alone or with tamsulosin, helps pass kidney stones faster and reduces pain better than current standard care.
What could go wrong
This is a phase 4 trial, so the drugs are already approved, but results may not apply to all stone types or sizes. Side effects like low blood pressure or urinary issues are possible.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Taipei Tzu Chi Hospital
RECRUITINGNew Taipei City, 231, Taiwan
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••