Can an amino acid help pass kidney stones better than a standard drug?

NCT ID NCT07617909

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares L-citrulline, an amino acid, to tamsulosin, a standard drug, for helping adults pass kidney stones. 120 people with a single stone in the lower ureter will take one of the two treatments for up to 4 weeks. The main goal is to see which treatment leads to faster stone passage with fewer symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
L-citrulline
What this could lead to
If it works, L-citrulline could offer a new option to help pass kidney stones without surgery.
What could go wrong
This is a small, early-phase trial. L-citrulline may not work as well as tamsulosin, and results may not apply to all stone types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Urology- Beni-Suef University Hospitals

    RECRUITING

    Banī Suwayf, Beni Suweif Governorate, 02456, Egypt

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